{"symbol":"THEMIS","synonyms":["BA325O24.3","SPOT","BA325O24.4","C6ORF190","C6ORF207","TSEPA"],"name":"thymocyte selection associated","description":"This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]","ncbiEntrezGeneId":387357,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/387357","proteins":[{"symbol":"THMS1_HUMAN","href":"/api/1.0/protein/THMS1_HUMAN"}],"hgncRootFamilies":[]}