{"symbol":"TIGIT","synonyms":["VSTM3","VSIG9","WUCAM"],"name":"T cell immunoreceptor with Ig and ITIM domains","description":"This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]","ncbiEntrezGeneId":201633,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/201633","proteins":[{"symbol":"TIGIT_HUMAN","href":"/api/1.0/protein/TIGIT_HUMAN"}],"hgncRootFamilies":[{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}