{"symbol":"TKTL1","synonyms":["TKR","TKT2"],"name":"transketolase-like 1","description":"The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]","ncbiEntrezGeneId":8277,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8277","proteins":[{"symbol":"TKTL1_HUMAN","href":"/api/1.0/protein/TKTL1_HUMAN"}],"hgncRootFamilies":[]}