{"symbol":"TLK2","synonyms":["MRD57","PKU-ALPHA","HSHPK"],"name":"tousled-like kinase 2","description":"This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]","ncbiEntrezGeneId":11011,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/11011","proteins":[{"symbol":"TLK2_HUMAN","href":"/api/1.0/protein/TLK2_HUMAN"}],"hgncRootFamilies":[]}