{"symbol":"TMBIM6","synonyms":["BAXI1","TEGT","BI-1"],"name":"transmembrane BAX inhibitor motif containing 6","description":"Enables endoribonuclease inhibitor activity and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of intrinsic apoptotic signaling pathway; negative regulation of macromolecule metabolic process; and response to L-glutamate. Acts upstream of or within negative regulation of calcium ion transport into cytosol. Located in endoplasmic reticulum membrane. Biomarker of cervical squamous cell carcinoma and prostate carcinoma. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":7009,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7009","proteins":[{"symbol":"BI1_HUMAN","href":"/api/1.0/protein/BI1_HUMAN"}],"hgncRootFamilies":[]}