{"symbol":"TMPRSS4","synonyms":["MT-SP2","TMPRSS3"],"name":"transmembrane protease, serine 4","description":"This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. The protein has been found to promote SARS-CoV-2 entry into host cells. [provided by RefSeq, Aug 2021]","ncbiEntrezGeneId":56649,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/56649","proteins":[{"symbol":"TMPS4_HUMAN","href":"/api/1.0/protein/TMPS4_HUMAN"}],"hgncRootFamilies":[{"name":"Proteases, serine (PRSS)","href":"/api/1.0/gene_family/Proteases%2C+serine+%28PRSS%29"}]}