{"symbol":"TNFRSF13B","synonyms":["CD267","TNFRSF14B","IGAD2","TACI","CVID","RYZN","CVID2"],"name":"tumor necrosis factor receptor superfamily, member 13B","description":"The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":23495,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23495","proteins":[{"symbol":"TR13B_HUMAN","href":"/api/1.0/protein/TR13B_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Tumor necrosis factor receptor superfamily (TNFRSF)","href":"/api/1.0/gene_family/Tumor+necrosis+factor+receptor+superfamily+%28TNFRSF%29"}]}