{"symbol":"TNFRSF14","synonyms":["ATAR","CD270","LIGHTR","HVEM","HVEA"],"name":"tumor necrosis factor receptor superfamily, member 14","description":"This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]","ncbiEntrezGeneId":8764,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8764","proteins":[{"symbol":"TNR14_HUMAN","href":"/api/1.0/protein/TNR14_HUMAN"}],"hgncRootFamilies":[{"name":"Tumor necrosis factor receptor superfamily (TNFRSF)","href":"/api/1.0/gene_family/Tumor+necrosis+factor+receptor+superfamily+%28TNFRSF%29"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}