{"symbol":"TNPO1","synonyms":["MIP1","IPO2","MIP","TRN","KPNB2"],"name":"transportin 1","description":"This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in several transcript variants encoding different proteins. [provided by RefSeq, Jun 2018]","ncbiEntrezGeneId":3842,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3842","proteins":[{"symbol":"TNPO1_HUMAN","href":"/api/1.0/protein/TNPO1_HUMAN"}],"hgncRootFamilies":[{"name":"Importins (IPO)","href":"/api/1.0/gene_family/Importins+%28IPO%29"}]}