{"symbol":"TNS3","synonyms":["TENS1","TEM6"],"name":"tensin 3","description":"Predicted to enable guanyl-nucleotide exchange factor adaptor activity. Predicted to be involved in positive regulation of Rac protein signal transduction and positive regulation of guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within several processes, including bone resorption; negative regulation of Rho protein signal transduction; and podosome assembly. Located in cytosol and focal adhesion. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":64759,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/64759","proteins":[{"symbol":"TENS3_HUMAN","href":"/api/1.0/protein/TENS3_HUMAN"}],"hgncRootFamilies":[{"name":"C2 domain containing","href":"/api/1.0/gene_family/C2+domain+containing"},{"name":"SH2 domain containing","href":"/api/1.0/gene_family/SH2+domain+containing"}]}