{"symbol":"TOLLIP","synonyms":["IL-1RACPIP"],"name":"toll interacting protein","description":"This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]","ncbiEntrezGeneId":54472,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/54472","proteins":[{"symbol":"TOLIP_HUMAN","href":"/api/1.0/protein/TOLIP_HUMAN"}],"hgncRootFamilies":[{"name":"C2 domain containing","href":"/api/1.0/gene_family/C2+domain+containing"}]}