{"symbol":"TOM1L2","synonyms":[],"name":"target of myb1-like 2 (chicken)","description":"This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain; domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Apr 2017]","ncbiEntrezGeneId":146691,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/146691","proteins":[{"symbol":"TM1L2_HUMAN","href":"/api/1.0/protein/TM1L2_HUMAN"}],"hgncRootFamilies":[]}