{"symbol":"TOX3","synonyms":["TNRC9","CAGF9"],"name":"TOX high mobility group box family member 3","description":"The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009]","ncbiEntrezGeneId":27324,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/27324","proteins":[{"symbol":"TOX3_HUMAN","href":"/api/1.0/protein/TOX3_HUMAN"}],"hgncRootFamilies":[{"name":"Trinucleotide repeat containing (TNRC)","href":"/api/1.0/gene_family/Trinucleotide+repeat+containing+%28TNRC%29"}]}