{"symbol":"TPK1","synonyms":["PP20","HTPK1","THMD5"],"name":"thiamin pyrophosphokinase 1","description":"The protein encoded by this gene functions as a homodimer and catalyzes the conversion of thiamine to thiamine pyrophosphate, a cofactor for some enzymes of the glycolytic and energy production pathways. Defects in this gene are a cause of thiamine metabolism dysfunction syndrome-5. [provided by RefSeq, Apr 2017]","ncbiEntrezGeneId":27010,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/27010","proteins":[{"symbol":"TPK1_HUMAN","href":"/api/1.0/protein/TPK1_HUMAN"}],"hgncRootFamilies":[]}