{"symbol":"TRAF5","synonyms":["RNF84","MGC:39780"],"name":"TNF receptor-associated factor 5","description":"The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]","ncbiEntrezGeneId":7188,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7188","proteins":[{"symbol":"TRAF5_HUMAN","href":"/api/1.0/protein/TRAF5_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}