{"symbol":"TRAF7","synonyms":["RFWD1","CAFDADD","RNF119"],"name":"TNF receptor-associated factor 7, E3 ubiquitin protein ligase","description":"Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.[supplied by OMIM, Apr 2004]","ncbiEntrezGeneId":84231,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/84231","proteins":[{"symbol":"TRAF7_HUMAN","href":"/api/1.0/protein/TRAF7_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"},{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}