{"symbol":"TRAPPC2","synonyms":["TRS20","HYP38334","TRAPPC2P1","ZNF547L","SEDT","SEDL"],"name":"trafficking protein particle complex 2","description":"The protein encoded by this gene is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]","ncbiEntrezGeneId":6399,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6399","proteins":[{"symbol":"TPC2A_HUMAN","href":"/api/1.0/protein/TPC2A_HUMAN"}],"hgncRootFamilies":[{"name":"Trafficking protein particle complex (TRAPPC)","href":"/api/1.0/gene_family/Trafficking+protein+particle+complex+%28TRAPPC%29"}]}