{"symbol":"TREM1","synonyms":["CD354","TREM-1"],"name":"triggering receptor expressed on myeloid cells 1","description":"This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]","ncbiEntrezGeneId":54210,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/54210","proteins":[{"symbol":"TREM1_HUMAN","href":"/api/1.0/protein/TREM1_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}