{"symbol":"TREX1","synonyms":["DRN3","HERNS","CRV"],"name":"three prime repair exonuclease 1","description":"This gene encodes a nuclear protein with 3\u0027 exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]","ncbiEntrezGeneId":11277,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/11277","proteins":[{"symbol":"TREX1_HUMAN","href":"/api/1.0/protein/TREX1_HUMAN"}],"hgncRootFamilies":[{"name":"Exonucleases","href":"/api/1.0/gene_family/Exonucleases"}]}