{"symbol":"TRHR","synonyms":["TRH-R"],"name":"thyrotropin-releasing hormone receptor","description":"This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011]","ncbiEntrezGeneId":7201,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7201","proteins":[{"symbol":"TRFR_HUMAN","href":"/api/1.0/protein/TRFR_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}