{"symbol":"TRIB1","synonyms":["TRB-1","C8FW","GIG2","GIG-2","TRB1","SKIP1"],"name":"tribbles pseudokinase 1","description":"Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; mitogen-activated protein kinase kinase binding activity; and protein kinase inhibitor activity. Involved in several processes, including JNK cascade; negative regulation of lipopolysaccharide-mediated signaling pathway; and regulation of protein kinase activity. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":10221,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10221","proteins":[{"symbol":"TRIB1_HUMAN","href":"/api/1.0/protein/TRIB1_HUMAN"}],"hgncRootFamilies":[]}