{"symbol":"TRIM22","synonyms":["RNF94","GPSTAF50","STAF50"],"name":"tripartite motif containing 22","description":"The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein is involved in innate immunity against different DNA and RNA viruses. [provided by RefSeq, Oct 2021]","ncbiEntrezGeneId":10346,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10346","proteins":[{"symbol":"TRI22_HUMAN","href":"/api/1.0/protein/TRI22_HUMAN"}],"hgncRootFamilies":[{"name":"Minor histocompatibility antigens","href":"/api/1.0/gene_family/Minor+histocompatibility+antigens"},{"name":"Tripartite motif-containing (TRIM)","href":"/api/1.0/gene_family/Tripartite+motif-containing+%28TRIM%29"},{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}