{"symbol":"TRIM28","synonyms":["TF1B","PPP1R157","TIF1B","RNF96"],"name":"tripartite motif containing 28","description":"The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":10155,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10155","proteins":[{"symbol":"TIF1B_HUMAN","href":"/api/1.0/protein/TIF1B_HUMAN"}],"hgncRootFamilies":[{"name":"Tripartite motif-containing (TRIM)","href":"/api/1.0/gene_family/Tripartite+motif-containing+%28TRIM%29"},{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"},{"name":"Protein phosphatase 1 regulatory subunits (PPP1R)","href":"/api/1.0/gene_family/Protein+phosphatase+1+regulatory+subunits+%28PPP1R%29"}]}