{"symbol":"TRIM8","synonyms":["RNF27","GERP"],"name":"tripartite motif containing 8","description":"This gene encodes a member of the tripartite motif (TRIM) protein family. Based on similarities to other proteins, the encoded protein is suspected to be an E3 ubiquitin-protein ligase. Regulation of this gene may be altered in some cancers. Mutations resulting in a truncated protein product have been observed in early-onset epileptic encephalopathy (EOEE). [provided by RefSeq, Sep 2016]","ncbiEntrezGeneId":81603,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/81603","proteins":[{"symbol":"TRIM8_HUMAN","href":"/api/1.0/protein/TRIM8_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"},{"name":"Tripartite motif-containing (TRIM)","href":"/api/1.0/gene_family/Tripartite+motif-containing+%28TRIM%29"}]}