{"symbol":"TRIP12","synonyms":["MRD49","TRIP-12","ULF"],"name":"thyroid hormone receptor interactor 12","description":"The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53. [provided by RefSeq, Jan 2017]","ncbiEntrezGeneId":9320,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9320","proteins":[{"symbol":"TRIPC_HUMAN","href":"/api/1.0/protein/TRIPC_HUMAN"}],"hgncRootFamilies":[]}