{"symbol":"TRMT12","synonyms":["TYW2","TRM12"],"name":"tRNA methyltransferase 12 homolog (S. cerevisiae)","description":"Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":55039,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55039","proteins":[{"symbol":"TYW2_HUMAN","href":"/api/1.0/protein/TYW2_HUMAN"}],"hgncRootFamilies":[]}