{"symbol":"TRPC1","synonyms":["HTRP-1"],"name":"transient receptor potential cation channel, subfamily C, member 1","description":"The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]","ncbiEntrezGeneId":7220,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7220","proteins":[{"symbol":"TRPC1_HUMAN","href":"/api/1.0/protein/TRPC1_HUMAN"}],"hgncRootFamilies":[{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}