{"symbol":"TRPV6","synonyms":["ZFAB","HSA277909","LP6728","ABP/ZF","ECAC2"],"name":"transient receptor potential cation channel, subfamily V, member 6","description":"This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds. [provided by RefSeq, Feb 2015]","ncbiEntrezGeneId":55503,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55503","proteins":[{"symbol":"TRPV6_HUMAN","href":"/api/1.0/protein/TRPV6_HUMAN"}],"hgncRootFamilies":[{"name":"Ankyrin repeat domain containing (ANKRD)","href":"/api/1.0/gene_family/Ankyrin+repeat+domain+containing+%28ANKRD%29"},{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}