{"symbol":"TSHR","synonyms":["LGR3","HTSHR-I","CHNG1"],"name":"thyroid stimulating hormone receptor","description":"The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]","ncbiEntrezGeneId":7253,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7253","proteins":[{"symbol":"TSHR_HUMAN","href":"/api/1.0/protein/TSHR_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}