{"symbol":"TSPAN4","synonyms":["TETRASPAN","TSPAN-4","TM4SF7","NAG-2","NAG2"],"name":"tetraspanin 4","description":"The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":7106,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7106","proteins":[{"symbol":"TSN4_HUMAN","href":"/api/1.0/protein/TSN4_HUMAN"}],"hgncRootFamilies":[{"name":"Tetraspanins (TSPAN)","href":"/api/1.0/gene_family/Tetraspanins+%28TSPAN%29"}]}