{"symbol":"TSPAN8","synonyms":["TM4SF3","CO-029"],"name":"tetraspanin 8","description":"The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":7103,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7103","proteins":[{"symbol":"TSN8_HUMAN","href":"/api/1.0/protein/TSN8_HUMAN"}],"hgncRootFamilies":[{"name":"Tetraspanins (TSPAN)","href":"/api/1.0/gene_family/Tetraspanins+%28TSPAN%29"}]}