{"symbol":"TTL","synonyms":[],"name":"tubulin tyrosine ligase","description":"TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003 [PubMed 14571137]).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":150465,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/150465","proteins":[{"symbol":"TTL_HUMAN","href":"/api/1.0/protein/TTL_HUMAN"}],"hgncRootFamilies":[]}