{"symbol":"UBAP1","synonyms":["UAP","UBAP-1","UBAP","NAG20"],"name":"ubiquitin associated protein 1","description":"This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]","ncbiEntrezGeneId":51271,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51271","proteins":[{"symbol":"UBAP1_HUMAN","href":"/api/1.0/protein/UBAP1_HUMAN"}],"hgncRootFamilies":[]}