{"symbol":"UBE2E1","synonyms":["UBCH6"],"name":"ubiquitin-conjugating enzyme E2E 1","description":"The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]","ncbiEntrezGeneId":7324,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7324","proteins":[{"symbol":"UB2E1_HUMAN","href":"/api/1.0/protein/UB2E1_HUMAN"}],"hgncRootFamilies":[{"name":"Ubiquitin-conjugating enzymes E2 (UBE2)","href":"/api/1.0/gene_family/Ubiquitin-conjugating+enzymes+E2+%28UBE2%29"}]}