{"symbol":"UBE2J1","synonyms":["CGI-76","HSPC153","HSPC205","UBC6","NCUBE-1","UBC6P","UBC6E","HSU93243","NCUBE1"],"name":"ubiquitin-conjugating enzyme E2, J1","description":"The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":51465,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51465","proteins":[{"symbol":"UB2J1_HUMAN","href":"/api/1.0/protein/UB2J1_HUMAN"}],"hgncRootFamilies":[{"name":"Ubiquitin-conjugating enzymes E2 (UBE2)","href":"/api/1.0/gene_family/Ubiquitin-conjugating+enzymes+E2+%28UBE2%29"}]}