{"symbol":"UBR4","synonyms":["RBAF600","ZUBR1"],"name":"ubiquitin protein ligase E3 component n-recognin 4","description":"The protein encoded by this gene is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. The encoded protein appears to be a cytoskeletal component in the cytoplasm and part of the chromatin scaffold in the nucleus. In addition, this protein is a target of the human papillomavirus type 16 E7 oncoprotein. [provided by RefSeq, Aug 2010]","ncbiEntrezGeneId":23352,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23352","proteins":[{"symbol":"UBR4_HUMAN","href":"/api/1.0/protein/UBR4_HUMAN"}],"hgncRootFamilies":[{"name":"Ubiquitin protein ligase E3 component n-recognins (UBR)","href":"/api/1.0/gene_family/Ubiquitin+protein+ligase+E3+component+n-recognins+%28UBR%29"}]}