{"symbol":"UCHL1","synonyms":["HEL-117","PARK5","PGP 9.5","HEL-S-53","NDGOA","PGP9.5","PGP95","UCH-L1","SPG79"],"name":"ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)","description":"The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]","ncbiEntrezGeneId":7345,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7345","proteins":[{"symbol":"UCHL1_HUMAN","href":"/api/1.0/protein/UCHL1_HUMAN"}],"hgncRootFamilies":[{"name":"Parkinson disease associated genes (PARK)","href":"/api/1.0/gene_family/Parkinson+disease+associated+genes+%28PARK%29"}]}