{"symbol":"UCN","synonyms":["UROC","UI"],"name":"urocortin","description":"This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family. The encoded preproprotein is proteolytically processed to generate the mature peptide, an endogenous ligand for both corticotropin-releasing factor receptor 1 and corticotropin-releasing factor receptor 2. In the brain this peptide may be responsible for the effects of stress on appetite. This peptide may also play a role in mood disorders, neurodegeneration, and skeletal system disorders. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin-2. [provided by RefSeq, Feb 2016]","ncbiEntrezGeneId":7349,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7349","proteins":[{"symbol":"UCN1_HUMAN","href":"/api/1.0/protein/UCN1_HUMAN"}],"hgncRootFamilies":[{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"}]}