{"symbol":"UFL1","synonyms":["NLBP","KIAA0776","MAXER"],"name":"UFM1-specific ligase 1","description":"Enables UFM1 ligase activity and protein kinase binding activity. Involved in several processes, including positive regulation of reticulophagy; regulation of intracellular signal transduction; and regulation of primary metabolic process. Acts upstream of or within several processes, including positive regulation of cell population proliferation; regulation of proteasomal ubiquitin-dependent protein catabolic process; and response to endoplasmic reticulum stress. Located in cytoplasm; nucleus; and site of double-strand break. Part of protein-containing complex. Is active in endoplasmic reticulum membrane and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":23376,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23376","proteins":[{"symbol":"UFL1_HUMAN","href":"/api/1.0/protein/UFL1_HUMAN"}],"hgncRootFamilies":[]}