{"symbol":"UNC5B","synonyms":["P53RDL1","UNC5H2"],"name":"unc-5 homolog B (C. elegans)","description":"This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]","ncbiEntrezGeneId":219699,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/219699","proteins":[{"symbol":"UNC5B_HUMAN","href":"/api/1.0/protein/UNC5B_HUMAN"}],"hgncRootFamilies":[{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}