{"symbol":"UPRT","synonyms":["FUR1"],"name":"uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)","description":"This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]","ncbiEntrezGeneId":139596,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/139596","proteins":[{"symbol":"UPP_HUMAN","href":"/api/1.0/protein/UPP_HUMAN"}],"hgncRootFamilies":[]}