{"symbol":"USO1","synonyms":["VDP"],"name":"USO1 vesicle transport factor","description":"The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]","ncbiEntrezGeneId":8615,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8615","proteins":[{"symbol":"USO1_HUMAN","href":"/api/1.0/protein/USO1_HUMAN"}],"hgncRootFamilies":[]}