{"symbol":"USP10","synonyms":["UBPO"],"name":"ubiquitin specific peptidase 10","description":"Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013]","ncbiEntrezGeneId":9100,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9100","proteins":[{"symbol":"UBP10_HUMAN","href":"/api/1.0/protein/UBP10_HUMAN"}],"hgncRootFamilies":[{"name":"Ubiquitin-specific peptidases (USP)","href":"/api/1.0/gene_family/Ubiquitin-specific+peptidases+%28USP%29"}]}