{"symbol":"USP16","synonyms":["UBP-M","UBPM"],"name":"ubiquitin specific peptidase 16","description":"This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":10600,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10600","proteins":[{"symbol":"UBP16_HUMAN","href":"/api/1.0/protein/UBP16_HUMAN"}],"hgncRootFamilies":[{"name":"Ubiquitin-specific peptidases (USP)","href":"/api/1.0/gene_family/Ubiquitin-specific+peptidases+%28USP%29"}]}