{"symbol":"USP27X","synonyms":["USP22L","USP27","MRX105"],"name":"ubiquitin specific peptidase 27, X-linked","description":"This gene encodes a member of the peptidase protein family. The encoded protein functions as a deubiquitinase that is involved in upregulation of the pro-apoptotic Bim protein. This protein may act as a tumor suppressor by increasing levels of Bim to counteract anti-apoptotic signals in cancer cells. Mutations in this gene have been associated with X-linked cognitive disability. [provided by RefSeq, Dec 2016]","ncbiEntrezGeneId":389856,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/389856","proteins":[{"symbol":"UBP27_HUMAN","href":"/api/1.0/protein/UBP27_HUMAN"}],"hgncRootFamilies":[{"name":"Ubiquitin-specific peptidases (USP)","href":"/api/1.0/gene_family/Ubiquitin-specific+peptidases+%28USP%29"}]}