{"symbol":"USP45","synonyms":[],"name":"ubiquitin specific peptidase 45","description":"The protein encoded by this gene is a deubiquitylase that binds ERCC1, the catalytic subunit of the XPF-ERCC1 DNA repair endonuclease. This endonuclease is a critical regulator of DNA repair processes, and the deubiquitylase activity of the encoded protein is important for maintaining the DNA repair ability of XPF-ERCC1. [provided by RefSeq, Sep 2016]","ncbiEntrezGeneId":85015,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/85015","proteins":[{"symbol":"UBP45_HUMAN","href":"/api/1.0/protein/UBP45_HUMAN"}],"hgncRootFamilies":[{"name":"Ubiquitin-specific peptidases (USP)","href":"/api/1.0/gene_family/Ubiquitin-specific+peptidases+%28USP%29"}]}