{"symbol":"VAMP1","synonyms":["VAMP-1","SYB1"],"name":"vesicle-associated membrane protein 1 (synaptobrevin 1)","description":"Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014]","ncbiEntrezGeneId":6843,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/6843","proteins":[{"symbol":"VAMP1_HUMAN","href":"/api/1.0/protein/VAMP1_HUMAN"}],"hgncRootFamilies":[{"name":"Vesicle-associated membrane proteins (VAMP)","href":"/api/1.0/gene_family/Vesicle-associated+membrane+proteins+%28VAMP%29"}]}