{"symbol":"VCAM1","synonyms":["INCAM-100","CD106"],"name":"vascular cell adhesion molecule 1","description":"This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]","ncbiEntrezGeneId":7412,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7412","proteins":[{"symbol":"VCAM1_HUMAN","href":"/api/1.0/protein/VCAM1_HUMAN"}],"hgncRootFamilies":[{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}