{"symbol":"VCX3A","synonyms":["VCX-A","VCXA","VCX3","VCX8R","VCX-8R"],"name":"variable charge, X-linked 3A","description":"This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":51481,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51481","proteins":[{"symbol":"VCX3_HUMAN","href":"/api/1.0/protein/VCX3_HUMAN"}],"hgncRootFamilies":[{"name":"Variable charge X/Y family (VCX, VCY)","href":"/api/1.0/gene_family/Variable+charge+X%24slash%24Y+family+%28VCX%2C+VCY%29"}]}