{"symbol":"VEGFB","synonyms":["VEGFL","VRF"],"name":"vascular endothelial growth factor B","description":"This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011]","ncbiEntrezGeneId":7423,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/7423","proteins":[{"symbol":"VEGFB_HUMAN","href":"/api/1.0/protein/VEGFB_HUMAN"}],"hgncRootFamilies":[]}